| Player | Comp/Att | Ps-Yards | Ps-TDs | int |
| Garoppolo, Jimmy | 17/28 | 322 | 0 | 0 |
|
| Player | Comp/Att | Ps-Yards | Ps-TDs | int |
| Fields, Justin | 19/27 | 175 | 1 | 1 |
|
| Player | Att | Yards | ave | TDs |
| Mitchell, Elijah | 18 | 137 | 7.6 | 1 |
| Garoppolo, Jimmy | 5 | 4 | 0.8 | 2 |
| Hasty, JaMycal | 3 | 4 | 1.3 | 0 |
|
| Player | Att | Yards | ave | TDs |
| Fields, Justin | 10 | 103 | 10.3 | 1 |
| Herbert, Khalil | 23 | 72 | 3.1 | 0 |
| Nall, Ryan | 1 | 4 | 4.0 | 0 |
| Williams, Damien | 2 | -3 | -1.5 | 0 |
|
| Player | T/Rec | Yards | ave | TDs |
| Samuel, Deebo | 9/6 | 171 | 28.5 | 0 |
| Sanu Sr., Mohamed | 4/3 | 59 | 19.7 | 0 |
| Aiyuk, Brandon | 7/4 | 45 | 11.3 | 0 |
| Hasty, JaMycal | 2/2 | 29 | 14.5 | 0 |
| Juszczyk, Kyle | 2/1 | 11 | 11.0 | 0 |
| Woerner, Charlie | 2/1 | 7 | 7.0 | 0 |
|
| Player | T/Rec | Yards | ave | TDs |
| Mooney, Darnell | 9/6 | 64 | 10.7 | 0 |
| James, Jesse | 3/3 | 38 | 12.7 | 1 |
| Goodwin, Marquise | 3/2 | 32 | 16.0 | 0 |
| Kmet, Cole | 6/3 | 24 | 8.0 | 0 |
| Robinson II, Allen | 4/3 | 21 | 7.0 | 0 |
| Herbert, Khalil | 2/2 | -4 | -2.0 | 0 |
|
| Player | XP/XA | FG/FGa | 1-39 | 40-49 | 50+ | FSV |
| Slye, Joey | 1/2 | 4/5 | 2/2 | 1/2 | 1/1 | 13 |
|
| Player | XP/XA | FG/FGa | 1-39 | 40-49 | 50+ | FSV |
| Santos, Cairo | 1/2 | 3/3 | 2/2 | 1/1 | 0/0 | 10 |
|
| Player | Fum | F lost | F Rec | F Forc | F TDs |
| Norman, Josh | 0 | 0 | 0 | 1 | 0 |
|
| Player | Fum | F lost | F Rec | F Forc | F TDs |
No Fumbles |
|
| Player | Int | Ret. Yds. | Ret. TDs |
| Norman, Josh | 1 | | 0 |
|
| Player | Int | Ret. Yds. | Ret. TDs |
No Interceptions |
|
| Player | Tackles | Assists | Sacks |
| Norman, Josh | 7 | 0 | 0 |
| Jones, D.J. | 5 | 0 | 0 |
| Harris, Marcell | 5 | 1 | 1 |
| Ward, Jimmie | 5 | 0 | 0 |
| Warner, Fred | 5 | 3 | 0 |
| Moseley, Emmanuel | 4 | 0 | 0 |
| Williams, K'Waun | 4 | 3 | 0 |
| Hufanga, Talanoa | 4 | 1 | 0 |
| Armstead, Arik | 3 | 1 | 0 |
| Bosa, Nick | 3 | 0 | 2 |
| Street, Kentavius | 2 | 0 | 0 |
| Ebukam, Samson | 2 | 0 | 1 |
| Key, Arden | 1 | 0 | 0 |
| Flannigan_Fowles, Demetrius | 1 | 1 | 0 |
| Givens, Kevin | 1 | 0 | 0 |
| Wilson Jr., Jeff | 0 | 1 | 0 |
| Wilson, Tavon | 0 | 1 | 0 |
|
| Player | Tackles | Assists | Sacks |
| Smith, Roquan | 5 | 1 | 0 |
| Houston_Carson, DeAndre | 5 | 1 | 0 |
| Ogletree, Alec | 3 | 2 | 0 |
| Hicks, Akiem | 3 | 1 | 0 |
| Johnson, Jaylon | 3 | 1 | 0 |
| Quinn, Robert | 2 | 1 | 0 |
| Trevathan, Danny | 2 | 2 | 0 |
| Vildor, Kindle | 2 | 0 | 0 |
| Gipson, Trevis | 2 | 2 | 0 |
| Gipson Sr., Tashaun | 2 | 3 | 0 |
| Tonga, Khyiris | 1 | 0 | 0 |
| Goldman, Eddie | 1 | 0 | 0 |
| Shelley, Duke | 0 | 1 | 0 |
| Kamara, Sam | 0 | 1 | 0 |
| Edwards Jr., Mario | 0 | 1 | 0 |
|
|
