The Facts: Coleman went on injured reserve with a knee sprain, keeping him out at least the next three games.

Diehards Line: The 49ers also will be without starter Raheem Mostert (knee sprain), so Jerick McKinnon’s workload should increase, along with Jeff Wilson Jr.’s power rushes and newly-promoted JaMycal Hasty’s change-of-pace speed. We'll have more on Coleman's progress, meanwhile, as he gets closer to a return after Week 6.