The Facts: According to ESPN.com's Adam Schefter, Reed will not play Sunday against the Chargers.

Diehards Line: Reed has now missed five straight games because of a hamstring injury, suffering a setback before the New Orleans game in Week 11. How he'll miss a sixth. The expectation was that he'd return at some point this season. It's been a bad year for Reed in terms of health –-- much more so than in previous seasons. Vernon Davis will continue to fill in.