The Facts: Deebo Samuel (who broke his foot Thursday) isn’t the only 49ers receiver to suffer an injury recently. Sources say James broke a bone in his wrist while training.

Diehards Line: With Samuel out three to four months and James likely to be sidelined at least two months, the onus is on Kendrick Bourne (30 receptions, 358 yards) as the 49ers' next-leading returning wideout. San Francisco will also look for contributions from 2020 first-round pick Brandon Aiyuk, 2019 third-rounder Jalen Hurd, who missed his entire rookie season with a back injury, and possibly Dante Pettis, who's caught just 38 passes over his first two seasons.