The Facts: Indianapolis Colts wide receiver Austin Collie regular season debut came to a premature end after he was injured making a 6-yard catch over the middle early in the third quarter. The crowd at Lucas Oil Stadium gasped when Collie went down and initially put his hands to his helmet. He laid on the ground for several minutes before he was helped off the field and to the locker room. Indy quickly confirmed that Collie sustained a right knee sprain and would not return.

Diehards Line:Collie hadn't seen many snaps before he went down with the knee injury, so it was clear the Colts were taking it easy with him. While it doesn't appear Collie's injury is particularly serious, his health concerns make it very difficult to count on him for fantasy purposes. Whether Collie's latest injury leads to additional missed time or not, fantasy owners may want to give Donnie Avery a look. Rookie T.Y. Hilton could potentially have value in deeper formats.