The Facts: Deebo Samuel (hamstring) and Jeff Wilson (ankle) have been ruled out for the rest of Week 7.

Diehards Line:Wilson was having a monstrous day, including three scores, before going down with a nasty ankle injury. Samuel was performing well too, with 65 yards on five catches. Both could have been ruled as a precaution because their game versus the Patriots is out of hand. If not, JaMycal Hasty and Brandon Aiyuk will take on larger roles in San Francisco's next game.