The Facts: At one point, there was hope the San Francisco 49ers would have Samuel for Week 1. Now, they're hoping he'll be back by the fourth week of the season as the 49ers placed Samuel on injured reserve Saturday, the team announced. Samuel is dealing with a Jones fracture he suffered in June.

Diehards Line: Samuel was ruled out on Friday for Sunday's game and his road to recovery is now a lot longer one. As a rookie in 2019, Samuel played an integral part in the 49ers ascent to the NFC West and NFC championships. He tallied 57 receptions for 802 yards and touchdowns. First-round rookie wideout Brandon Aiyuk (hamstring) is also questionable for Sunday as the 49ers' WR corps continue to be in a woeful state with injuries. As NFL.com notes, Jalen Hurd (ACL) is out for the year, Travis Benjamin opted out, Richie James is dealing with a wrist injury and Tavon Austin (who was signed as reinforcements to the rash of injuries) is out for the year.