The Facts: 49ers running back Matt Breida will miss Week 14 with an ankle injury.

Diehards Line:Breida aggravated the ankle injury he has been battling for most of the season, during pregame warmups on Sunday. He was able to play through it, but did not make much of an impact. Jeff Wilson received the bulk of the workload against Seattle and will likely see the majority of the work in Week 14 against the Broncos. Wilson should be considered a priority waiver wire addition this week and can be considered a borderline RB3 against the Broncos.