| Player | Comp/Att | Ps-Yards | Ps-TDs | int |
| Garoppolo, Jimmy | 17/25 | 296 | 3 | 1 |
| Pettis, Dante | 1/1 | 16 | 0 | 0 |
|
| Player | Comp/Att | Ps-Yards | Ps-TDs | int |
| Falk, Luke | 20/25 | 198 | 0 | 0 |
| Siemian, Trevor | 3/6 | 3 | 0 | 0 |
|
| Player | Att | Yards | ave | TDs |
| Breida, Matt | 12 | 121 | 10.1 | 0 |
| Mostert, Raheem | 13 | 83 | 6.4 | 0 |
| Wilson Jr., Jeff | 10 | 34 | 3.4 | 2 |
| Garoppolo, Jimmy | 4 | 8 | 2.0 | 0 |
| Samuel, Deebo | 2 | 7 | 3.5 | 0 |
| Juszczyk, Kyle | 1 | 6 | 6.0 | 0 |
|
| Player | Att | Yards | ave | TDs |
| Bell, Le'Veon | 21 | 68 | 3.2 | 0 |
| Montgomery, Ty | 3 | 25 | 8.3 | 0 |
|
| Player | T/Rec | Yards | ave | TDs |
| Samuel, Deebo | 7/5 | 86 | 17.2 | 1 |
| Goodwin, Marquise | 3/3 | 77 | 25.7 | 1 |
| Mostert, Raheem | 4/3 | 68 | 22.7 | 1 |
| Kittle, George | 3/3 | 54 | 18.0 | 0 |
| Breida, Matt | 1/1 | 11 | 11.0 | 0 |
| James Jr., Richie | 4/1 | 7 | 7.0 | 0 |
| Juszczyk, Kyle | 2/1 | 5 | 5.0 | 0 |
| Bourne, Kendrick | 2/1 | 4 | 4.0 | 0 |
|
| Player | T/Rec | Yards | ave | TDs |
| Anderson, Robby | 6/4 | 81 | 20.3 | 0 |
| Bell, Le'Veon | 10/10 | 61 | 6.1 | 0 |
| Crowder, Jamison | 6/4 | 40 | 10.0 | 0 |
| Montgomery, Ty | 3/3 | 15 | 5.0 | 0 |
| Bellamy, Josh | 2/1 | 5 | 5.0 | 0 |
| Thomas, Demaryius | 2/1 | -1 | -1.0 | 0 |
|
| Player | XP/XA | FG/FGa | 1-39 | 40-49 | 50+ | FSV |
| Gould, Robbie | 5/5 | 2/3 | 2/3 | 0/0 | 0/0 | 11 |
|
| Player | XP/XA | FG/FGa | 1-39 | 40-49 | 50+ | FSV |
| Ficken, Sam | 0/0 | 1/1 | 0/0 | 1/1 | 0/0 | 3 |
|
| Player | Fum | F lost | F Rec | F Forc | F TDs |
No Fumbles |
|
| Player | Fum | F lost | F Rec | F Forc | F TDs |
No Fumbles |
|
| Player | Int | Ret. Yds. | Ret. TDs |
| Alexander, Kwon | 1 | | 0 |
|
| Player | Int | Ret. Yds. | Ret. TDs |
| Roberts, Darryl | 1 | | 0 |
|
| Player | Tackles | Assists | Sacks |
| Warner, Fred | 4 | 3 | 0 |
| Blair III, Ronald | 4 | 1 | 1 |
| Alexander, Kwon | 3 | 3 | 0 |
| Williams, K'Waun | 3 | 4 | 0 |
| Witherspoon, Ahkello | 3 | 2 | 0 |
| Moore, Tarvarius | 2 | 2 | 0 |
| Reed Jr., D.J. | 2 | 1 | 0 |
| Sherman, Richard | 2 | 2 | 0 |
| Tartt, Jaquiski | 2 | 3 | 0 |
| Thomas, Solomon | 2 | 1 | 1 |
| Armstead, Arik | 2 | 1 | 1 |
| Toilolo, Levine | 1 | 0 | 0 |
| Greenlaw, Dre | 1 | 2 | 0 |
| Buckner, DeForest | 1 | 0 | 1 |
| Day, Sheldon | 1 | 1 | 0 |
| Al_Shaair, Azeez | 0 | 1 | 0 |
| Ford, Dee | 0 | 1 | 0 |
|
| Player | Tackles | Assists | Sacks |
| Adams, Jamal | 5 | 0 | 0 |
| Roberts, Darryl | 4 | 1 | 0 |
| Hewitt, Neville | 3 | 4 | 1 |
| Kaufusi, Bronson | 2 | 1 | 0.5 |
| Maye, Marcus | 2 | 0 | 0 |
| Fatukasi, Folorunso | 2 | 0 | 0 |
| Poole, Brian | 2 | 1 | 0 |
| Cashman, Blake | 2 | 4 | 0.5 |
| Hairston, Nate | 2 | 1 | 0 |
| Miles, Rontez | 1 | 0 | 0 |
| Phillips, Kyle | 1 | 1 | 0 |
| Basham, Tarell | 1 | 3 | 1 |
| McLendon, Steve | 1 | 4 | 0 |
| Anderson, Henry | 0 | 2 | 0 |
| Jenkins, Jordan | 0 | 1 | 0 |
| Langi, Harvey | 0 | 1 | 0 |
| Williams, Leonard | 0 | 2 | 0 |
|
|
