The Facts: Lattimore has reached a crossroads in his comeback quest. NFL Network's Ian Rapoport reported Sunday that the running back is weighing his options after experiencing soreness in his surgically repaired right knee and legs, according to a team sources and a source close to the player. Lattimore was not on the sidelines during Sunday's 13-10 loss to the St. Louis Rams. "(I) did not see Marcus," HC Jim Harbaugh said during his Sunday postgame news conference. "I'm sure we'll have an announcement about that."

Diehards Line: Lattimore returned to practice this week, a big step forward in his attempted comeback from a devastating knee injury suffered during his final college season at South Carolina. He moved well in practice on Wednesday and Thursday, but sat out Friday's practice when soreness developed. The 49ers invested a 2013 fourth-round pick in Lattimore, who rehabbed the knee during his rookie season and was expected to contribute this season. "Nobody knows Marcus' body like Marcus, so he has to think some things over," a source told CSNBayArea.com. ... Stay tuned.